SCHEMBL8147277

SCHEMBL8147277

FC1=CCC(F)(c2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.35
MAOA P21397 4/20 0.35
HDAC4 P56524 1/20 0.31
HTR2A P28223 2/20 0.30
HTR2C P28335 2/20 0.30
HTR2B P41595 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15103023 0.79 MAOB (0.38) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL5715764 0.72 MAOB (0.38) MAOBMAOAHDAC4HTR2AHTR2C
SCHEMBL28919330 0.71 MAOB (0.36) MAOBMAOAHDAC4HTR2AHTR2C
SCHEMBL6426369 0.69 MAOB (0.46) MAOBMAOAHDAC4HTR2AHTR2C
SCHEMBL7612888 0.66 MAOB (0.38) MAOBMAOAHDAC4HTR2AHTR2C
SCHEMBL29269286 0.65 MAOA (0.35) MAOBMAOA
SCHEMBL5658399 0.64
SCHEMBL19717526 0.62 MAOB (0.62) MAOBMAOAHTR2AHTR2CHTR2B
SCHEMBL4457208 0.60
SCHEMBL3979553 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070864-A1 METHOD FOR PRODUCING AROMATIC COMPOUND HAVING FLUOROALKYL GROUP DAIKIN INDUSTRIES, LTD. (JP) 2026-03-12 US disclosed
EP-4685127-A1 METHOD FOR PRODUCING AROMATIC COMPOUND HAVING FLUOROALKYL GROUP Daikin Industries, Ltd. (JP) 2026-01-28 EP disclosed
WO-2024237156-A1 METHOD FOR PRODUCING AROMATIC COMPOUND HAVING FLUOROALKYL GROUP ダイキン工業株式会社 2024-11-21 WO disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070864-A1 METHOD FOR PRODUCING AROMATIC COMPOUND HAVING FLUOROALKYL GROUP AFF1, NAF1, AFF2 MAOB 1848/4885MAOA 2418/4885HDAC4 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.