SCHEMBL29269286

SCHEMBL29269286

FC1=CCC(Cl)(Cc2ccccc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.35
MAOB P27338 4/20 0.35
KDM1A O60341 3/20 0.32
RCOR1 Q9UKL0 1/20 0.32
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29269303 0.76 MAOA (0.33) MAOAMAOB
SCHEMBL8147277 0.65 MAOB (0.35) MAOAMAOB
SCHEMBL8308764 0.61 MAOA (0.36) MAOAMAOBKDM1A
SCHEMBL31357393 0.61 CYP3A4 (0.33) MAOAMAOBKDM1ARCOR1
SCHEMBL9120691 0.60 MAOA (0.46) MAOAMAOBKDM1ARCOR1
SCHEMBL2347654 0.57 MAOA (0.43) MAOAMAOBKDM1ARCOR1
SCHEMBL5811976 0.56 KDM1A (0.61) MAOAMAOBKDM1ARCOR1
SCHEMBL2810084 0.56 MAOA (0.52) MAOAMAOBKDM1AGAA
SCHEMBL2808245 0.55 GAA (0.58) MAOAMAOBPOLBGAA
SCHEMBL5802127 0.55 MAOA (0.50) MAOAMAOBKDM1ARCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307456-A Coniferyl aldehyde derivative containing dithioacetal unit, and preparation method and application thereof 贵州大学 2024-07-09 CN disclosed