Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.30 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.30 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.30 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.30 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.30 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814189 | 0.86 | KDM4E (0.31) | ALDH1A1HPGDKDM4EPOLBTDP1 | |
| SCHEMBL813758 | 0.85 | KDM4E (0.31) | ALDH1A1HPGDKDM4EPOLBTDP1 | |
| SCHEMBL813791 | 0.82 | NPC1 (0.36) | ALDH1A1HPGDKDM4EPOLBTDP1 | |
| SCHEMBL12460048 | 0.81 | RAB9A (0.35) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL814180 | 0.80 | LMNA (0.32) | ALDH1A1POLB | |
| SCHEMBL814526 | 0.79 | MAPT (0.36) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL813953 | 0.78 | MEN1 (0.35) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL814334 | 0.77 | GAA (0.32) | ALDH1A1HPGDKDM4EPOLBTDP1 | |
| SCHEMBL814053 | 0.77 | ALDH1A1 (0.33) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL814656 | 0.76 | KDM4E (0.31) | ALDH1A1HPGDKDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603957-B1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | INEOS SALES UK LTD (GB) | 2015-10-28 | — | — | EP | disclosed |
| US-8067328-B2 | Polymerisation and oligomerisation catalysts | INEOS EUROPE LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-7989565-B2 | Polyolefins | INEOS EUROPE LIMITED (GB) | 2011-08-02 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124487-A1 | Polyolefins | BARCLAYS BANK PLC (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-20070207918-A1 | Polymerisation and Oligomerisation Catalysts | INEOS SALES (UK) LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |