Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 3/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150375 | 1.00 | DGAT1 (0.42) | DGAT1KDM1AKDM1BNNMTGPR27 | |
| SCHEMBL8154315 | 0.88 | DGAT1 (0.40) | DGAT1NNMTHDAC1HDAC6BTK | |
| SCHEMBL8150396 | 0.88 | NNMT (0.40) | DGAT1NNMTBTKSIRT3TDP1 | |
| SCHEMBL17786864 | 0.86 | DGAT1 (0.47) | DGAT1KDM1AKDM1BNNMTGPR27 | |
| SCHEMBL8150440 | 0.83 | KDM1A (0.39) | KDM1AKDM1B | |
| SCHEMBL8155519 | 0.83 | KDM1A (0.39) | KDM1AKDM1B | |
| SCHEMBL8155345 | 0.80 | CASP1 (0.38) | DGAT1NNMTGPR27MEN1KMT2A | |
| SCHEMBL8141774 | 0.80 | CASP1 (0.38) | DGAT1NNMTGPR27MEN1KMT2A | |
| SCHEMBL8155379 | 0.80 | POLB (0.38) | NNMTMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8149546 | 0.80 | POLB (0.38) | NNMTMAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |