Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | CEL | P19835 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601781 | 0.98 | MAOA (0.39) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL18695663 | 0.70 | NR1I2 (0.33) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL1414158 | 0.64 | CYP11B2 (0.31) | TDO2CYP11B2 | |
| SCHEMBL10781942 | 0.64 | MAOA (0.64) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL28720 | 0.61 | MAOA (0.44) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL14603709 | 0.61 | DAO (0.33) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL8885354 | 0.61 | MAOA (0.44) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL4696964 | 0.61 | DAO (0.33) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL9250741 | 0.61 | MAOA (0.44) | MAOAMAOBDAOPTPN1PTPRC | |
| SCHEMBL21335045 | 0.61 | DAO (0.39) | MAOAMAOBDAOPTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011052-A | Pyrazolone derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2000-01-04 | — | — | US | disclosed |