Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198890 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1MAPTAPOBEC3ARECQL | |
| SCHEMBL14255598 | 0.78 | — | — | |
| SCHEMBL18154850 | 0.77 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTLMNARECQL | |
| SCHEMBL1831917 | 0.77 | — | — | |
| SCHEMBL7869498 | 0.77 | — | — | |
| SCHEMBL25978088 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL25009530 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1LMNA | |
| SCHEMBL17187510 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1MAPTAPOBEC3ARECQL | |
| SCHEMBL25978090 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL8143727 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |