SCHEMBL18154850

SCHEMBL18154850

CC1=NCCCN1CCCN(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
LMNA P02545 3/20 0.33
MAPT P10636 2/20 0.33
CHRM2 P08172 2/20 0.33
HTR1A P08908 2/20 0.33
CHRM5 P08912 2/20 0.33
DRD2 P14416 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
CHRM3 P20309 2/20 0.33
DRD4 P21917 2/20 0.33
SLC6A2 P23975 2/20 0.33
HRH2 P25021 2/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
ADRA1A P35348 2/20 0.33
HRH1 P35367 2/20 0.33
DRD3 P35462 2/20 0.33
OPRK1 P41145 2/20 0.33
HTR2B P41595 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19803147 0.91 PIM1 (0.32) PIM1
SCHEMBL22068835 0.82 KDM4E (0.36) ALDH1A1LMNACYP2D6KDM4ETSHR
SCHEMBL17424836 0.81 TSHR (0.43) ALDH1A1LMNACYP2D6KDM4ETSHR
SCHEMBL22769465 0.80 KDM4E (0.32) ALDH1A1KDM4ETSHRHTT
SCHEMBL11135987 0.80 KDM4E (0.32) ALDH1A1KDM4ESMN1; SMN2TSHRHTT
SCHEMBL19803146 0.79 KDM4E (0.31) ALDH1A1KDM4ETSHRHTT
SCHEMBL11121197 0.79 ALDH1A1 (0.43) ALDH1A1MAPTCYP2D6GAATSHR
SCHEMBL8149059 0.77 KDM4E (0.40) ALDH1A1LMNAMAPTKDM4EGLA
SCHEMBL246647 0.77 CYP2D6 (0.38) ALDH1A1LMNACYP2D6KDM4ETSHR
SCHEMBL18986133 0.76 KDM4E (0.33) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448552-B2 Adhesive bond between a thermoplastic material and an elastomer composition SIKA TECHNOLOGY AG (CH) 2025-10-21 US disclosed
US-12240960-B2 Thixotropic agent for curable compositions SIKA TECHNOLOGY AG (CH) 2025-03-04 US disclosed
US-12157707-B2 Curable composition for alkaline substrates SIKA TECHNOLOGY AG (CH) 2024-12-03 US disclosed
EP-3880728-B1 ADHESIVE BOND BETWEEN THERMOPLASTIC AND ELASTOMER COMPOSITION SIKA TECH AG (CH) 2024-10-30 EP disclosed
CN-112912414-B Adhesive bond between thermoplastic and elastomeric compositions SIKA技术股份公司 2023-10-20 CN disclosed
EP-3880729-B1 THIXOTROPIC AGENTS FOR CURABLE COMPOSITIONS SIKA TECH AG (CH) 2023-09-27 EP disclosed
CN-112839917-B Curable composition for alkaline substrates SIKA技术股份公司 2023-08-08 CN disclosed
CN-112955485-B Thixotropic agents for curable compositions SIKA技术股份公司 2023-08-08 CN disclosed
CN-109563232-B Two-component polyurethane adhesive with mechanical properties substantially unaffected by temperature and high strength SIKA技术股份公司 2022-04-12 CN disclosed
US-20220041838-A1 THIXOTROPIC AGENT FOR CURABLE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2022-02-10 US disclosed
US-10392480-B2 Catalyst containing amidine groups SIKA TECHNOLOGY AG (CH) 2019-08-27 US disclosed
WO-2019145420-A1 CURABLE COMPOSITION COMPRISING AN ACETAL PLASTICIZER SIKA TECHNOLOGY AG (CH) 2019-08-01 WO disclosed
EP-3494155-A1 TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH Sika Technology AG (CH) 2019-06-12 EP disclosed
US-20190169354-A1 TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH SIKA TECHNOLOGY AG (CH) 2019-06-06 US disclosed
CN-109563232-A With the mechanical performance not being affected by temperature substantially and high-intensitive two component polyurethane adhesive SIKA技术股份公司 2019-04-02 CN disclosed
EP-3339295-A1 AMIDINE CATALYST FOR CURABLE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2018-06-27 EP disclosed
US-20180171082-A1 CATALYST CONTAINING AMIDINE GROUPS SIKA TECHNOLOGY AG (CH) 2018-06-21 US disclosed
EP-3283550-A1 AMIDINE-GROUP CONTAINING CATALYST Sika Technology AG (CH) 2018-02-21 EP disclosed
EP-3279231-A1 TWO COMPONENT POLYURETHANE ADHESIVE WITH SUBSTANTIALLY TEMPERATURE DEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH Sika Technology AG (CH) 2018-02-07 EP disclosed
WO-2016166336-A1 AMIDINE-GROUP CONTAINING CATALYST SIKA TECHNOLOGY AG (CH) 2016-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240960-B2 Thixotropic agent for curable compositions INCENP, GJA1, RCC1 ALDH1A1 1682/4885LMNA 3647/4885MAPT 89/4885
US-20220041838-A1 THIXOTROPIC AGENT FOR CURABLE COMPOSITIONS INCENP, GJA1, RCC1 ALDH1A1 1682/4885LMNA 3647/4885MAPT 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.