SCHEMBL814962

SCHEMBL814962

[C](c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.52
ALDH1A1 P00352 7/20 0.50
HSD17B10 Q99714 5/20 0.50
CYP2A6 P11509 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CYP1A2 P05177 6/20 0.48
HPGD P15428 3/20 0.48
THRB P10828 1/20 0.48
CYP3A4 P08684 2/20 0.46
ABCB11 O95342 1/20 0.46
NR3C1 P04150 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX15 P16050 1/20 0.46
ADRA2C P18825 1/20 0.46
MAOA P21397 1/20 0.46
DRD1 P21728 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10804459 1.00 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL1141298 1.00 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL1141385 0.85 CHAT (0.44) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL1141388 0.85 CHAT (0.44) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL10432886 0.85 CHAT (0.44) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL103697 0.84 ALDH1A1 (0.48) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL29661843 0.83 CHAT (0.60) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL2776015 0.83 CHAT (0.60) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL6364668 0.81 CHAT (0.58) HPRT1ALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL507946 0.79 CA1 (0.47) HPRT1ALDH1A1HSD17B10CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108841379-A A kind of preparation method of the OLED hole transport new material suitable for solution processing 刘坤 2018-11-20 CN claimed
EP-0098982-B1 PHOTOPOLYMERIZABLE MIXTURE, AND PHOTOPOLYMERIZABLE COPYING MATERIAL PRODUCED THEREWITH HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-06 EP claimed
US-4458006-A PRINTING PLATES HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-03 US claimed
CN-112703210-B Preparation of bimodal rubbers, thermoplastic vulcanizates, and articles made therefrom 埃克森美孚化学专利公司 2022-10-28 CN disclosed
US-11352453-B2 Catalyst for olefin polymerization and production method for polar group-containing olefin-based polymers THE UNIVERSITY OF TOKYO (JP) 2022-06-07 US disclosed
CN-113166519-A Blends of cyclic olefin copolymers and films made therefrom 埃克森美孚化学专利公司 2021-07-23 CN disclosed
CN-112703210-A Preparation of bimodal rubbers, thermoplastic vulcanizates, and articles made therefrom 埃克森美孚化学专利公司 2021-04-23 CN disclosed
US-20200347159-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR POLAR GROUP-CONTAINING OLEFIN-BASED POLYMERS THE UNIVERSITY OF TOKYO (JP) 2020-11-05 US disclosed
EP-3708593-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR POLAR GROUP-CONTAINING OLEFIN-BASED POLYMERS The University Of Tokyo (JP) 2020-09-16 EP disclosed
US-20200247925-A1 4-METHYL-1-PENTENE/alpha-OLEFIN COPOLYMER, COMPOSITION COMPRISING THE COPOLYMER AND 4-METHYL-1-PENTENE COPOLYMER COMPOSITION MITSUI CHEMICALS, INC. (JP) 2020-08-06 US disclosed
US-10662270-B2 4-methyl-1-pentene/α-olefin copolymer, composition comprising the copolymer and 4-methyl-1-pentene copolymer composition MITSUI CHEMICALS, INC. (JP) 2020-05-26 US disclosed
EP-1064311-A1 HIGH TEMPERATURE OLEFIN POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 2001-01-03 EP disclosed
EP-1062254-A1 POLYMERIZATION PROCESS FOR OLEFIN COPOLYMERS USING BRIDGED HAFNOCENE COMPOUNDS EXXON CHEMICAL PATENTS INC. (US) 2000-12-27 EP disclosed
US-6121396-A USING A METALLOCENE HAVING A SUBSTITUTED FLUORENYL GROUP, AND A COMPOUND REACTING WITH THE METALLOCENE TO FORM A CATIONIC METALLOCENE; HIGH- AND NARROW MOLECULAR WEIGHT; NARROW COMPOSITION DISTRIBUTION; PROCESS TEMPERATURE OF >120 C. TOSOH CORPORATION (JP) 2000-09-19 US disclosed
WO-1999045041-A1 HIGH TEMPERATURE OLEFIN POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 1999-09-10 WO disclosed
WO-1999045040-A1 POLYMERIZATION PROCESS FOR OLEFIN COPOLYMERS USING BRIDGED HAFNOCENE COMPOUNDS EXXON CHEMICAL PATENTS INC. (US) 1999-09-10 WO disclosed
EP-0709393-A2 Olefin polymerization catalyst and process for producing olefin polymer TOSOH CORPORATION (JP) 1996-05-01 EP disclosed
EP-0230609-A1 Resinous composition GENERAL ELECTRIC COMPANY (US) 1987-08-05 EP disclosed
US-4458006-A PRINTING PLATES HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-03 US disclosed
US-4458006-A PRINTING PLATES HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200347159-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR POLAR GROUP-CONTAINING OLEFIN-BASED POLYMERS POF1B, COG1, ACOX1 HPRT1 3394/4885ALDH1A1 1604/4885HSD17B10 643/4885
US-11352453-B2 Catalyst for olefin polymerization and production method for polar group-containing olefin-based polymers POF1B, COG1, ACOX1 HPRT1 3394/4885ALDH1A1 1604/4885HSD17B10 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.