Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141575 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11102418 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8404534 | 0.86 | CYP2A6 (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL15131700 | 0.81 | CYP3A4 (0.61) | ALDH1A1MAPTKDM4ETERTCYP3A4 | |
| SCHEMBL28755396 | 0.78 | TERT (0.64) | ALDH1A1MAPTKDM4ETERTCYP3A4 | |
| SCHEMBL18623484 | 0.78 | CYP3A4 (0.58) | ALDH1A1MAPTKDM4ETERTCYP3A4 | |
| SCHEMBL22173826 | 0.78 | CYP3A4 (0.67) | ALDH1A1MAPTKDM4ETERTCYP3A4 | |
| SCHEMBL15131712 | 0.78 | TERT (0.64) | ALDH1A1MAPTKDM4ETERTCYP3A4 | |
| SCHEMBL22142547 | 0.77 | TERT (0.52) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5748750 | 0.77 | TERT (0.52) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |