Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265489 | 0.88 | ENPP2 (0.58) | USP2ACACBMAPTALDH1A1HRH1 | |
| SCHEMBL6272036 | 0.85 | NR4A2 (0.51) | RXRARXRBUSP2ACACBMAPT | |
| SCHEMBL6272089 | 0.85 | ENPP2 (0.55) | MAPTALDH1A1HRH1CCR3KCNH2 | |
| Hydrochloric Acid SCHEMBL9032597 | 0.84 | ENPP2 (0.54) | MAPTALDH1A1HRH1CCR3KCNH2 | |
| SCHEMBL6272295 | 0.82 | NR4A2 (0.48) | RXRARXRBUSP2ACACBMAPT | |
| SCHEMBL6266696 | 0.81 | ENPP2 (0.56) | MAPTALDH1A1ENPP2PARP15PARP10 | |
| SCHEMBL23698044 | 0.81 | USP2 (0.57) | USP2MAPTALDH1A1HRH1CCR3 | |
| SCHEMBL6270830 | 0.78 | MAPT (0.47) | RXRARXRBUSP2MAPTALDH1A1 | |
| SCHEMBL20893533 | 0.77 | POLB (0.53) | MAPTALDH1A1KDM4ENPSR1RBP4 | |
| SCHEMBL20893534 | 0.77 | POLB (0.53) | MAPTALDH1A1KDM4ENPSR1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |