Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731647 | 0.76 | RAB9A (0.59) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL10636018 | 0.75 | POLB (0.61) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL1828531 | 0.75 | HSD17B10 (0.56) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL15413676 | 0.75 | HSD17B10 (0.56) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL3804451 | 0.75 | ALDH1A1 (0.59) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL4010104 | 0.74 | HSD17B10 (0.55) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL25931269 | 0.73 | HSD17B10 (0.50) | HSD17B10POLBALDH1A1CYP2C9KMT2A | |
| SCHEMBL400161 | 0.73 | POLB (0.70) | HSD17B10POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1029180 | 0.72 | HSD17B10 (1.00) | HSD17B10ALDH1A1CYP2C9KMT2AMEN1 | |
| SCHEMBL430583 | 0.72 | POLB (0.63) | HSD17B10POLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000005246-A1 | THIOAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | HOECHST MARION ROUSSEL (FR) | 2000-02-03 | — | — | WO | disclosed |