SCHEMBL8151002

SCHEMBL8151002

Oc1cccc(-c2ccccc2)c1C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HPGD P15428 1/20 0.50
BCL2L1 Q07817 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
BACE1 P56817 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
POLB P06746 1/20 0.41
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butanone SCHEMBL28338079 0.87 ALDH1A1 (0.41) ALDH1A1HPGDBCL2L1HSD17B10MEN1
SCHEMBL7531576 0.82 HDAC4 (0.50) ALDH1A1HPGDHSD17B10MEN1KMT2A
SCHEMBL6004412 0.82 HDAC4 (0.50) ALDH1A1HPGDHSD17B10MEN1KMT2A
SCHEMBL4476579 0.82 CHRNB2 (0.57) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL28816105 0.82 CHRNB2 (0.57) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
2-Phenylphenol SCHEMBL28139423 0.81 ALDH1A1 (0.59) ALDH1A1HPGDBCL2L1HSD17B10MEN1
Phosphine SCHEMBL2085260 0.81 CHRNB2 (0.59) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL3169205 0.80 HDAC4 (0.52) ALDH1A1HPGDBCL2L1HSD17B10MEN1
SCHEMBL9306107 0.80 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL27995875 0.80 CHRNB2 (0.58) ALDH1A1MEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107522827-A A kind of photocuring 3D printing photosensitive resin and its preparation method and application 杨军 2017-12-29 CN claimed
WO-2000001139-A1 SILYLATION LAYER FOR OPTICAL DEVICES INTEL CORPORATION (US) 2000-01-06 WO claimed