SCHEMBL81512

SCHEMBL81512

ClCc1nc(CCl)nc(CCl)n1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
JAK2 O60674 2/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9078634 0.83 CASP1 (0.46) NPC1RAB9AJAK2MAPTHTT
SCHEMBL10907064 0.78 ALDH1A1 (0.53)
SCHEMBL2117455 0.75 KMT2A (0.32) KMT2A
SCHEMBL2363476 0.75
SCHEMBL27906532 0.75 CASP1 (0.52) NPC1RAB9AJAK2MAPTHTT
SCHEMBL10710919 0.71
SCHEMBL11012026 0.71
SCHEMBL2117448 0.71
SCHEMBL14143667 0.67 CASP1 (0.32)
SCHEMBL874436 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025046146-A1 POLYPEPTIDE SCREENING Bicycle TX Limited (GB) 2025-03-06 WO claimed
US-20230350293-A1 I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR REDUCING HEIGHT DIFFERENCE BETWEEN CENTER AND EDGE AND REDUCING LER, AND I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR IMPROVING PROCESS MARGIN YOUNG CHANG CHEMICAL CO., LTD (KR) 2023-11-02 US claimed
EP-4220301-A1 I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR REDUCING HEIGHT DIFFERENCE BETWEEN CENTER AND EDGE AND REDUCING LER, AND I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR IMPROVING PROCESS MARGIN Young Chang Chemical Co., Ltd. (KR) 2023-08-02 EP claimed
CN-116194842-A Negative photoresist composition for I-line for improving step difference and LER between center and edge, and negative photoresist composition for I-line for improving process margin 荣昌化学制品株式会社 2023-05-30 CN claimed
WO-2022065713-A1 I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR REDUCING HEIGHT DIFFERENCE BETWEEN CENTER AND EDGE AND REDUCING LER, AND I-LINE NEGATIVE PHOTORESIST COMPOSITION FOR IMPROVING PROCESS MARGIN 영창케미칼 주식회사 2022-03-31 WO claimed
CN-110128570-A Dendritic photosensitizer, synthetic method and the application of the segment containing benzidion 郑州工程技术学院 2019-08-16 CN claimed
US-20180246404-A1 I-LINE NEGATIVE TYPE PHOTORESIST COMPOSITION HAVING EXCELLENT ETCHING RESISTANCE YCCHEM CO., LTD. (KR) 2018-08-30 US claimed
CN-107924124-A Negative photoresist composition for I-line with excellent etching resistance 荣昌化学制品株式会社 2018-04-17 CN claimed
CN-105152945-A Triphenylamine visible light photosensitizer containing two aromatic substituent groups and application thereof UNIV CHONGQING 2015-12-16 CN claimed
CN-105061642-A Naphthol photosensitizer containing aliphatic chain fragment, and synthesis and application thereof UNIV CHONGQING 2015-11-18 CN claimed
CN-104877057-A Coumarin fragment-containing benzotriazole photosensitizer and synthesis and application thereof UNIV CHONGQING 2015-09-02 CN claimed
CN-104693323-A Naphthalene nucleus contained visible light photosensitizer of conjugated structure and application thereof UNIV CHONGQING 2015-06-10 CN claimed
CN-104693322-A Phenyl vinyl imino group class visible light photosensitizer of conjugated structure and application thereof UNIV CHONGQING 2015-06-10 CN claimed
CN-102558397-B Benzotriazole near ultraviolet photosensitizer with conjugation structure as well as synthesis and application of benzotriazole near ultraviolet photosensitizer UNIV CHONGQING 2013-06-12 CN claimed
US-20030176520-A1 4-cyanocoumarin derivatives and uses thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2003-09-18 US claimed
US-20020052501-A1 4-cyanocoumarin derivatives and uses thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2002-05-02 US claimed
EP-1041074-A1 Light-sensitive 4-cyanocoumarin derivatives KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2000-10-04 EP claimed
JP-63273686-A None JP disclosed
US-4481276-A ARGON LASER FUJI PHOTO FILM CO., LTD. (JP) 1984-11-06 US disclosed
US-4259432-A HIGH SENSITIVITY TO ULTRAVIOLET RADIATION AND ARGON LASER RAYS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176520-A1 4-cyanocoumarin derivatives and uses thereof CACYBP, CYBA, IK NPC1 4286/4885RAB9A 4409/4885JAK2 2333/4885
US-20020052501-A1 4-cyanocoumarin derivatives and uses thereof CACYBP, CYBA, IK NPC1 4286/4885RAB9A 4409/4885JAK2 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.