Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204365 | 0.79 | AKR1B1 (0.39) | TAAR1AKR1B1SMN1; SMN2POLBKDM4E | |
| SCHEMBL6204367 | 0.79 | AKR1B1 (0.39) | TAAR1AKR1B1SMN1; SMN2POLBKDM4E | |
| SCHEMBL5018858 | 0.75 | TAAR1 (0.44) | TAAR1AKR1B1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL11566859 | 0.72 | AKR1B1 (0.48) | TAAR1AKR1B1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL2426412 | 0.71 | AKR1B1 (0.43) | TAAR1AKR1B1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL15083012 | 0.71 | AKR1B1 (0.43) | TAAR1AKR1B1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL13692457 | 0.71 | SLC6A2 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL11276473 | 0.71 | SLC6A2 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL18537078 | 0.71 | TAAR1 (0.41) | TAAR1AKR1B1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL4796836 | 0.70 | SMN1; SMN2 (0.48) | TAAR1AKR1B1SMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000327674-A | 4-HALOBENZOFURAN DERIVATIVE AND ITS PRODUCTION | TOSOH CORP | 2000-11-28 | — | — | JP | disclosed |