Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156192 | 0.93 | POLB (0.44) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8152937 | 0.86 | PSEN1 (0.39) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8157085 | 0.85 | TDP1 (0.43) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8381808 | 0.85 | TDP1 (0.43) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8157079 | 0.84 | MEN1 (0.46) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8150938 | 0.83 | HTT (0.47) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8144639 | 0.83 | TBXAS1 (0.40) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8157309 | 0.83 | CA1 (0.40) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL8152330 | 0.82 | CYP3A4 (0.46) | POLBAPEX1HTTTDP1ALOX5 | |
| SCHEMBL9340619 | 0.82 | CYP3A4 (0.46) | POLBAPEX1HTTTDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |