Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153415 | 0.93 | ALOX5 (0.42) | PSEN1ALOX5PTGESPPARGPSEN2 | |
| SCHEMBL8157079 | 0.86 | MEN1 (0.46) | ALOX5PTGESPPARGAKR1C3DPEP1 | |
| SCHEMBL8152711 | 0.86 | POLB (0.40) | ALOX5PTGESPPARGEPHX2POLB | |
| SCHEMBL8157309 | 0.85 | CA1 (0.40) | ALOX5AKR1C3POLBAPEX1HTT | |
| SCHEMBL8152330 | 0.84 | CYP3A4 (0.46) | ALOX5PTGESPPARGAKR1C3POLB | |
| SCHEMBL9340619 | 0.84 | CYP3A4 (0.46) | ALOX5PTGESPPARGAKR1C3POLB | |
| SCHEMBL8153430 | 0.84 | GRIK1 (0.46) | ALOX5AKR1C3PPARAPOLBAPEX1 | |
| SCHEMBL8380576 | 0.84 | GRIK1 (0.46) | ALOX5AKR1C3PPARAPOLBAPEX1 | |
| SCHEMBL8144639 | 0.82 | TBXAS1 (0.40) | ALOX5PTGESPPARGAKR1C3POLB | |
| SCHEMBL8157085 | 0.82 | TDP1 (0.43) | ALOX5AKR1C3POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |