SCHEMBL8153041

SCHEMBL8153041

Nc1cc(F)c(F)c(Oc2cc(Oc3cc(N)cc(F)c3F)c(C(F)(F)F)c(C(F)(F)F)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.32
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8151728 0.88 ALDH1A1 (0.31)
SCHEMBL8146839 0.88 GLA (0.36) AR
SCHEMBL8152815 0.86 AR (0.32) AR
SCHEMBL8152244 0.84 AR (0.40) ARKIF11
SCHEMBL8151984 0.83 GLA (0.31) KIF11
SCHEMBL8143697 0.83 GAA (0.38) ARKIF11
SCHEMBL8138066 0.82 ALDH1A1 (0.31)
SCHEMBL8145810 0.82 KIF11 (0.35) ARKIF11
SCHEMBL8137137 0.82 ALDH1A1 (0.34)
SCHEMBL8147984 0.81 KIF11 (0.31) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed