Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160080 | 0.98 | SMN1; SMN2 (0.35) | SMN1; SMN2APPTSHRLTA4HKDM4E | |
| SCHEMBL8159899 | 0.95 | SMN1; SMN2 (0.33) | SMN1; SMN2APPTSHRLTA4HKDM4E | |
| SCHEMBL8158074 | 0.93 | SMN1; SMN2 (0.34) | SMN1; SMN2APPTSHRLTA4HKDM4E | |
| SCHEMBL8773423 | 0.89 | TSHR (0.37) | SMN1; SMN2TSHRLTA4HKDM4EALDH1A1 | |
| Carbon Monoxide SCHEMBL11109139 | 0.88 | APP (0.31) | SMN1; SMN2APPTSHRLTA4H | |
| SCHEMBL8934009 | 0.86 | TSHR (0.38) | SMN1; SMN2TSHRLTA4HKDM4EALDH1A1 | |
| Fluoride SCHEMBL27518867 | 0.85 | TSHR (0.37) | SMN1; SMN2TSHRLTA4HKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27537336 | 0.85 | TSHR (0.37) | SMN1; SMN2TSHRLTA4HKDM4EALDH1A1 | |
| SCHEMBL10964720 | 0.81 | POLB (0.38) | SMN1; SMN2TSHRKDM4EALDH1A1LMNA | |
| Tetrabuthylammonium SCHEMBL15345895 | 0.79 | CA12 (0.36) | TSHRALDH1A1MMP13TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149868-A | Carbonylation process | SHELL OIL COMPANY (US) | 1992-09-22 | — | — | US | claimed |
| EP-0805139-B1 | HYDROFORMYLATION METHOD | KURARAY CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5773666-A | CARRYING OUT REACTION IN THE PRESENCE OF A RHODIUM COMPOUND, A TERTIARY ORGANIC PHOSPHINE AND A POLAR ORGANIC COMPOUND | KURARAY CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0805139-A1 | HYDROFORMYLATION METHOD | KURARAY CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0489472-B1 | Carbonylation process and catalyst composition | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | EP | disclosed |
| US-5149868-A | Carbonylation process | SHELL OIL COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0489472-A2 | Carbonylation process and catalyst composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-10 | — | — | EP | disclosed |
| US-4940683-A | Polymerization process | SHELL OIL COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4855399-A | Carbon monoxide/olefin co-polymerization process with phosphino substituted sulfonic acid catalyst | SHELL OIL COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4001017-A | REDOX CATALYSTS, DIAZINES, ELECTRON DONORS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |