SCHEMBL8934009

SCHEMBL8934009

O=S(=O)(O)CCP(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ACP1 P24666 2/20 0.33
CYP3A4 P08684 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2C9 P11712 1/20 0.33
LMNA P02545 2/20 0.32
BLM P54132 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
GFER P55789 1/20 0.32
PMP22 Q01453 1/20 0.32
HSD11B1 P28845 1/20 0.32
SRC P12931 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27518867 0.98 TSHR (0.37) TSHRSMN1; SMN2ACP1CYP3A4TDP1
Hydrochloric Acid SCHEMBL27537336 0.98 TSHR (0.37) TSHRSMN1; SMN2ACP1CYP3A4TDP1
SCHEMBL8773423 0.98 TSHR (0.37) TSHRSMN1; SMN2ACP1CYP3A4TDP1
SCHEMBL8160080 0.88 SMN1; SMN2 (0.35) TSHRSMN1; SMN2CYP3A4TDP1CYP2C19
SCHEMBL8158074 0.86 SMN1; SMN2 (0.34) TSHRSMN1; SMN2CYP3A4TDP1CYP2C19
SCHEMBL8153480 0.86 SMN1; SMN2 (0.34) TSHRSMN1; SMN2CYP3A4TDP1CYP2C19
SCHEMBL8159899 0.85 SMN1; SMN2 (0.33) TSHRSMN1; SMN2LMNAKDM4EALDH1A1
Carbon Monoxide SCHEMBL11109139 0.82 APP (0.31) TSHRSMN1; SMN2LTA4H
SCHEMBL28052482 0.79 TDP1 (0.38) CYP3A4TDP1ALDH1A1CA1CA2
SCHEMBL27518864 0.79 FAAH (0.43) CYP3A4TDP1CA1CA2PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022128833-A1 SOLID TRANSITION METAL-LIGAND COMPLEXES MERCK PATENT GMBH (DE) 2022-06-23 WO claimed
WO-1996026177-A1 PROCESS FOR PREPARING ARYLACETIC ACID AND ARYLPROPIONIC ACID DERIVATIVES HOECHST CELANESE CORPORATION (US) 1996-08-29 WO claimed
US-5536874-A Process for preparing arylacetic acid and arylpropionic acid derivatives HOECHST CELANESE CORPORATION (US) 1996-07-16 US claimed
EP-0694522-A2 Process for preparing arylacetic acid derivatives by carbonylation of arylmethylhalogenids HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP claimed
EP-0280380-B1 CATALYST COMPOSITIONS AND PROCESS FOR COPOLYMERIZING CO WITH ONE OR MORE OLEFINICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-12 EP claimed
EP-0280380-A2 Catalyst compositions and process for copolymerizing Co with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-31 EP claimed
WO-2022128833-A1 SOLID TRANSITION METAL-LIGAND COMPLEXES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-1996026177-A1 PROCESS FOR PREPARING ARYLACETIC ACID AND ARYLPROPIONIC ACID DERIVATIVES HOECHST CELANESE CORPORATION (US) 1996-08-29 WO disclosed
US-5536874-A Process for preparing arylacetic acid and arylpropionic acid derivatives HOECHST CELANESE CORPORATION (US) 1996-07-16 US disclosed
EP-0357101-B1 Copolymers of carbon monoxide SHELL INT RESEARCH (NL) 1996-02-28 EP disclosed
EP-0694522-A2 Process for preparing arylacetic acid derivatives by carbonylation of arylmethylhalogenids HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP disclosed
EP-0285218-B1 Removal of catalyst remnants from olefin/CO copolymers SHELL INT RESEARCH (NL) 1994-12-21 EP disclosed
CN-1021451-C Process for removing catalyst residues from olefin/carbon monoxide copolymers SHELL INT RESEARCH (NL) 1993-06-30 CN disclosed
EP-0349084-A2 Polyketone derived products SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-01-03 EP disclosed
US-4855400-A Removal of catalyst residues from carbon monoxide/olefin polymers with catalyst complexing agent SHELL OIL COMPANY (US) 1989-08-08 US disclosed
CN-88101593-A Process for removing catalyst residues from olefin/carbon monoxide copolymers 1988-11-30 CN disclosed
EP-0285218-A2 Removal of catalyst remnants from olefin/CO copolymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-05 EP disclosed
EP-0283092-A1 Process for removing palladium catalyst remnants from copolymers of carbon monoxide with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-09-21 EP disclosed
CN-88101227-A The method of from the multipolymer of carbon monoxide and one or more alefinically unsaturated compounds, removing palladium catalyst remants 1988-09-21 CN disclosed
EP-0280380-A2 Catalyst compositions and process for copolymerizing Co with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-31 EP disclosed