SCHEMBL8160080

SCHEMBL8160080

O=S(=O)(O)CCCP(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.35
APP P05067 1/20 0.35
TSHR P16473 1/20 0.35
LTA4H P09960 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
PKM P14618 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CYP3A4 P08684 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
GFER P55789 1/20 0.31
PMP22 Q01453 1/20 0.31
MMP13 P45452 1/20 0.30
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153480 0.98 SMN1; SMN2 (0.34) SMN1; SMN2APPTSHRLTA4HALDH1A1
SCHEMBL8158074 0.94 SMN1; SMN2 (0.34) SMN1; SMN2APPTSHRLTA4HALDH1A1
SCHEMBL8159899 0.93 SMN1; SMN2 (0.33) SMN1; SMN2APPTSHRLTA4HALDH1A1
Carbon Monoxide SCHEMBL11109139 0.90 APP (0.31) SMN1; SMN2APPTSHRLTA4H
SCHEMBL8934009 0.88 TSHR (0.38) SMN1; SMN2TSHRLTA4HALDH1A1KDM4E
SCHEMBL8773423 0.86 TSHR (0.37) SMN1; SMN2TSHRLTA4HALDH1A1KDM4E
Hydrochloric Acid SCHEMBL27537336 0.86 TSHR (0.37) SMN1; SMN2TSHRLTA4HALDH1A1KDM4E
Fluoride SCHEMBL27518867 0.86 TSHR (0.37) SMN1; SMN2TSHRLTA4HALDH1A1KDM4E
SCHEMBL10964720 0.82 POLB (0.38) SMN1; SMN2TSHRALDH1A1KDM4ELMNA
Tetrabuthylammonium SCHEMBL15345895 0.81 CA12 (0.36) TSHRALDH1A1TDP1MMP13CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022128833-A1 SOLID TRANSITION METAL-LIGAND COMPLEXES MERCK PATENT GMBH (DE) 2022-06-23 WO claimed
EP-3169431-A1 HIGH EFFICIENCY, ULTRA-STABLE, BONDED HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC) MATRIX ON SUPERFICIALLY POROUS PARTICLES (SPPS) Azyp LLC (US) 2017-05-24 EP claimed
WO-2016011427-A1 HIGH EFFICIENCY, ULTRA-STABLE, BONDED HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC) MATRIX ON SUPERFICIALLY POROUS PARTICLES (SPPS) AZYP, LLC (US) 2016-01-21 WO claimed
EP-0350922-B1 Process for catalyst-aldehyde product separation UNION CARBIDE CHEM PLASTIC (US) 1994-09-21 EP claimed
EP-0280380-B1 CATALYST COMPOSITIONS AND PROCESS FOR COPOLYMERIZING CO WITH ONE OR MORE OLEFINICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-12 EP claimed
EP-0280380-A2 Catalyst compositions and process for copolymerizing Co with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-31 EP claimed
WO-2022128833-A1 SOLID TRANSITION METAL-LIGAND COMPLEXES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
CN-114292295-A Method for synthesizing organic phosphine sulfonate derivative 河南省科学院化学研究所有限公司 2022-04-08 CN disclosed
EP-3169431-A1 HIGH EFFICIENCY, ULTRA-STABLE, BONDED HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC) MATRIX ON SUPERFICIALLY POROUS PARTICLES (SPPS) Azyp LLC (US) 2017-05-24 EP disclosed
WO-2016011427-A1 HIGH EFFICIENCY, ULTRA-STABLE, BONDED HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC) MATRIX ON SUPERFICIALLY POROUS PARTICLES (SPPS) AZYP, LLC (US) 2016-01-21 WO disclosed
US-20080112866-A1 Functionalized ionic liquids, and methods of use thereof UNIVERSITY OF SOUTH ALABAMA (US) 2008-05-15 US disclosed
EP-0805139-B1 HYDROFORMYLATION METHOD KURARAY CO (JP) 2000-04-26 EP disclosed
US-5773666-A CARRYING OUT REACTION IN THE PRESENCE OF A RHODIUM COMPOUND, A TERTIARY ORGANIC PHOSPHINE AND A POLAR ORGANIC COMPOUND KURARAY CO., LTD. (JP) 1998-06-30 US disclosed
CN-88101593-A Process for removing catalyst residues from olefin/carbon monoxide copolymers 1988-11-30 CN disclosed
EP-0285218-A2 Removal of catalyst remnants from olefin/CO copolymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-05 EP disclosed
EP-0283092-A1 Process for removing palladium catalyst remnants from copolymers of carbon monoxide with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-09-21 EP disclosed
CN-88101227-A The method of from the multipolymer of carbon monoxide and one or more alefinically unsaturated compounds, removing palladium catalyst remants 1988-09-21 CN disclosed
EP-0280380-A2 Catalyst compositions and process for copolymerizing Co with one or more olefinically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-31 EP disclosed
US-4357280-A Use of tertiary phosphines in photographic silver dye bleach materials CIBA-GEIGY AG (CH) 1982-11-02 US disclosed
US-4138256-A Method of processing photographic silver dye bleach materials CIBA-GEIGY AG (CH) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080112866-A1 Functionalized ionic liquids, and methods of use thereof TST, SCLY, MPST SMN1; SMN2 1737/4885APP 3919/4885TSHR 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.