Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934009 | 0.98 | TSHR (0.38) | TSHRSMN1; SMN2ACP1CYP3A4TDP1 | |
| Fluoride SCHEMBL27518867 | 0.96 | TSHR (0.37) | TSHRSMN1; SMN2ACP1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL27537336 | 0.96 | TSHR (0.37) | TSHRSMN1; SMN2ACP1CYP3A4TDP1 | |
| SCHEMBL8153480 | 0.89 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2CYP3A4TDP1CYP2C9 | |
| SCHEMBL8159899 | 0.87 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8160080 | 0.86 | SMN1; SMN2 (0.35) | TSHRSMN1; SMN2CYP3A4TDP1CYP2C9 | |
| SCHEMBL8158074 | 0.85 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2CYP3A4TDP1CYP2C9 | |
| Carbon Monoxide SCHEMBL11109139 | 0.80 | APP (0.31) | TSHRSMN1; SMN2LTA4H | |
| SCHEMBL27722081 | 0.78 | CA2 (0.43) | CA1CA2 | |
| SCHEMBL28052482 | 0.78 | TDP1 (0.38) | CYP3A4TDP1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489472-B1 | Carbonylation process and catalyst composition | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | EP | disclosed |
| EP-0296550-B1 | Phosphonium salts and processes for production of and uses for the same | KURARAY CO (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5149868-A | Carbonylation process | SHELL OIL COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0489472-A2 | Carbonylation process and catalyst composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-10 | — | — | EP | disclosed |
| US-5100854-A | Telomerization catalysts | KURARAY CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4992609-A | Telomerization catalysts | KURARAY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4927960-A | TELOMERIZATION CATALYST | KURARAY COMPANY, LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0296550-A2 | Phosphonium salts and processes for production of and uses for the same | KURARAY CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |