Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155126 | 0.88 | KDM4E (0.55) | KDM4ESMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL8147041 | 0.83 | NPC1 (0.65) | SMN1; SMN2GAAMAPTALDH1A1PTGS2 | |
| SCHEMBL8153628 | 0.82 | KMT2A (0.60) | KDM4ESMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL8148914 | 0.81 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL8141155 | 0.81 | L3MBTL1 (0.67) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2829560 | 0.81 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL8153641 | 0.79 | KDM4E (0.41) | KDM4ESMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL14190938 | 0.78 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL4377582 | 0.78 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL13636009 | 0.78 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |