Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984153 | 0.89 | ADORA2A (0.38) | VKORC1KCNH2KDM4ELMNAHTT | |
| SCHEMBL6976958 | 0.89 | GUSB (0.37) | VKORC1KCNH2KDM4ELMNAHTT | |
| SCHEMBL6977489 | 0.88 | GABRA1 (0.41) | VKORC1KCNH2HTTCYP1A2CYP3A4 | |
| SCHEMBL8159124 | 0.88 | GABRA5 (0.41) | SRCALDH1A1GABRA1GABRA5 | |
| SCHEMBL6974694 | 0.88 | PTGDR2 (0.45) | SRC | |
| SCHEMBL6979201 | 0.88 | GABRA1 (0.41) | VKORC1KDM4EHTTCYP1A2CYP3A4 | |
| SCHEMBL6979014 | 0.86 | GABRA1 (0.41) | KDM4EHTTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8151315 | 0.86 | KDM4E (0.41) | KDM4ELMNAHTTTSHRCYP1A2 | |
| SCHEMBL6982751 | 0.85 | GABRA5 (0.38) | VKORC1CYP3A4SRCALDH1A1GABRA1 | |
| SCHEMBL7666493 | 0.85 | GABRA1 (0.40) | VKORC1KCNH2KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |