Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982751 | 0.94 | GABRA5 (0.38) | GABRA5GABRA1EGFRALDH1A1SRC | |
| SCHEMBL7670695 | 0.89 | GABRA5 (0.43) | GABRA5GABRA1EGFRALDH1A1SNCA | |
| SCHEMBL6974694 | 0.88 | PTGDR2 (0.45) | SRCPKMGRIN1GRIN2BTBXAS1 | |
| SCHEMBL6979201 | 0.88 | GABRA1 (0.41) | GABRA5GABRA1ALDH1A1SRCPKM | |
| SCHEMBL8153648 | 0.88 | VKORC1 (0.40) | GABRA5GABRA1ALDH1A1SRC | |
| SCHEMBL6981471 | 0.87 | GABRA5 (0.43) | GABRA5GABRA1EGFRALDH1A1PKM | |
| SCHEMBL6975094 | 0.86 | GABRA5 (0.38) | GABRA5GABRA1EGFRSRCPKM | |
| SCHEMBL6975201 | 0.85 | GABRA1 (0.43) | GABRA5GABRA1ALDH1A1TBXAS1PTAFR | |
| SCHEMBL6971385 | 0.83 | CYP19A1 (0.43) | GABRA5GABRA1ALDH1A1 | |
| SCHEMBL6977489 | 0.82 | GABRA1 (0.41) | GABRA5GABRA1ALDH1A1SRCPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |