Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160845 | 0.90 | THRB (0.31) | THRB | |
| SCHEMBL8161131 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL8161125 | 0.77 | — | — | |
| SCHEMBL15312406 | 0.75 | THRB (0.36) | THRB | |
| SCHEMBL65281 | 0.75 | THRB (0.53) | THRB | |
| SCHEMBL28808158 | 0.73 | TSHR (0.39) | THRB | |
| SCHEMBL137795 | 0.72 | TSHR (0.53) | THRB | |
| SCHEMBL9705690 | 0.72 | CYP1A2 (0.42) | — | |
| SCHEMBL466667 | 0.72 | — | — | |
| SCHEMBL28311835 | 0.72 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708143-B1 | Polyvinyl chloride based resin composition and products derived therefrom | SEKISUI AMERICA CORP (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0708143-A1 | Polyvinyl chloride based resin composition and products derived therefrom | SEKISUI AMERICA CORPORATION (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0413310-A2 | Thermoplastic resin composition having improved impact resistance | MITSUBISHI RAYON CO., LTD (JP) | 1991-02-20 | — | — | EP | disclosed |
| EP-0231776-A1 | Thermoplastic polyester resin composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-08-12 | — | — | EP | disclosed |