SCHEMBL8160845

SCHEMBL8160845

C=C(C)C(=O)C(=O)CCC[SiH2]C(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153740 0.90 THRB (0.33) THRB
SCHEMBL28311835 0.80 CYP1A2 (0.32)
SCHEMBL8154700 0.78
SCHEMBL3900735 0.78 TBXAS1 (0.32)
SCHEMBL28808158 0.78 TSHR (0.39) THRBTSHR
SCHEMBL137795 0.76 TSHR (0.53) THRBTSHR
SCHEMBL876650 0.75 TSHR (0.56) THRBTSHR
SCHEMBL21066734 0.74 TSHR (0.58) THRBTSHR
SCHEMBL27511005 0.74 TSHR (0.58) THRBTSHR
SCHEMBL16537548 0.74 TSHR (0.58) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708143-B1 Polyvinyl chloride based resin composition and products derived therefrom SEKISUI AMERICA CORP (US) 2000-01-05 EP disclosed