Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667572 | 0.98 | MEN1 (0.51) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL10621050 | 0.98 | MEN1 (0.51) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8778447 | 0.98 | MEN1 (0.51) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL20415949 | 0.91 | CYP3A4 (0.43) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL11360893 | 0.84 | PTPN11 (0.50) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8167721 | 0.83 | PTPN11 (0.61) | PTPN11S1PR3TP53TSHRPLA2G2A | |
| SCHEMBL8421089 | 0.82 | PLK1 (0.50) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL20472214 | 0.82 | MEN1 (0.51) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL20472402 | 0.82 | PTPN11 (0.51) | CYP3A4MEN1NR1I2LMNACHRM2 | |
| SCHEMBL25258360 | 0.82 | MEN1 (0.50) | CYP3A4MEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488093-A | Stiff-chain polyesters and a method of preparing them | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1996-01-30 | — | — | US | claimed |
| EP-0890615-B1 | High temperature crosslinkable liquid crystalline polyester compositions | DAINIPPON INK & CHEMICALS (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0890615-A1 | High temperature crosslinkable liquid crystalline polyester compositions | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5488093-A | Stiff-chain polyesters and a method of preparing them | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1996-01-30 | — | — | US | disclosed |