Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449519 | 0.87 | PTPN11 (0.63) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL11287767 | 0.84 | MRGPRX1 (0.49) | CYP3A4ALDH1A1 | |
| SCHEMBL11360893 | 0.84 | PTPN11 (0.50) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8154031 | 0.82 | CYP3A4 (0.49) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL20472402 | 0.82 | PTPN11 (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL7366543 | 0.81 | LMNA (0.69) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8778447 | 0.81 | MEN1 (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL667572 | 0.81 | MEN1 (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10621050 | 0.81 | MEN1 (0.51) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8982612 | 0.80 | LMNA (0.72) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018148204-A1 | ASK1 INHIBITING AGENTS | BIOGEN MA INC. (US) | 2018-08-16 | — | — | WO | disclosed |