SCHEMBL25258360

SCHEMBL25258360

CCCCCOc1cc(C(=O)NN)c(OCCCCC)cc1C(=O)NN

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NR1I2 O75469 1/20 0.50
LMNA P02545 1/20 0.50
CHRM2 P08172 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
MAPT P10636 1/20 0.50
OPRK1 P41145 1/20 0.50
HTR2B P41595 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
SMPD1 P17405 5/20 0.48
NPSR1 Q6W5P4 1/20 0.46
S1PR3 Q99500 1/20 0.43
PTPN11 Q06124 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31122217 0.98 MEN1 (0.53) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL28418266 0.96 MEN1 (0.45) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL29419922 0.92 PTPN11 (0.54) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL22568081 0.89 MAPT (0.47) MEN1KMT2ALMNACYP3A4MAPT
SCHEMBL26355068 0.85 THRA (0.54) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL30569533 0.82 MEN1 (0.45) MEN1KMT2AMAPT
SCHEMBL31007082 0.82 KMT2A (0.49) MEN1KMT2ACYP3A4MAPT
SCHEMBL8154031 0.82 CYP3A4 (0.49) MEN1KMT2ANR1I2LMNACHRM2
SCHEMBL18045688 0.82 TSHR (0.58) MEN1KMT2ACYP3A4MAPT
SCHEMBL5083225 0.81 KMT2A (0.73) MEN1KMT2ANR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376060-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) 2024-11-14 US claimed
EP-4460504-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-11-13 EP claimed
WO-2023131977-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2023-07-13 WO claimed
US-20240376060-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) 2024-11-14 US disclosed
EP-4460504-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-11-13 EP disclosed
WO-2023131977-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2023-07-13 WO disclosed
WO-2023131977-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2023-07-13 WO disclosed
CN-111363145-A Covalent organic framework material and synthesis method and application thereof 临沂大学 2020-07-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376060-A1 A SMART COVALENT ORGANIC FRAMEWORK AND A PROCESS FOR CARBON DIOXIDE ADSORPTION INDUCED SWITCHABLE ANTIBACTERIAL ACTIVITY THEREFROM EEF2, CTSF, TUFM MEN1 3952/4885KMT2A 1481/4885NR1I2 3757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.