Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965645 | 0.72 | KDM4C (0.40) | GPR84POLBTAAR1APAF1KDM4C | |
| SCHEMBL14401328 | 0.71 | GAA (0.44) | GPR84ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL2181657 | 0.71 | GPR84 (0.50) | GPR84ALDH1A1LMNACA1 | |
| SCHEMBL3497870 | 0.70 | MEN1 (0.62) | GPR84POLBAPAF1KDM4CALDH1A1 | |
| SCHEMBL14450261 | 0.70 | GAA (0.70) | KDM4CALDH1A1LMNAHPGDGAA | |
| SCHEMBL1362732 | 0.66 | GPR84 (0.53) | GPR84ALDH1A1LMNACA1 | |
| SCHEMBL193916 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4GAAKDM4E | |
| SCHEMBL1792016 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4GAAKDM4E | |
| SCHEMBL21650526 | 0.66 | NOTUM (0.48) | ALDH1A1HPGDCYP3A4 | |
| SCHEMBL28818278 | 0.65 | GPR84 (0.51) | GPR84ALDH1A1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | disclosed |