SCHEMBL1362732

SCHEMBL1362732

CN(C)c1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 9/20 0.53
CA1 P00915 1/20 0.50
ALDH1A1 P00352 2/20 0.40
DAO P14920 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.39
YTHDF3 Q7Z739 1/20 0.39
YTHDF1 Q9BYJ9 1/20 0.39
YTHDF2 Q9Y5A9 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
PIK3CB P42338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28818278 0.98 GPR84 (0.51) GPR84CA1ALDH1A1DAOLMNA
SCHEMBL2181657 0.82 GPR84 (0.50) GPR84CA1ALDH1A1LMNACYP1A2
SCHEMBL3475870 0.74 GPR84 (0.44) GPR84CA1ALDH1A1LMNACYP1A2
SCHEMBL27312293 0.73 GAA (0.46) GPR84CA1ALDH1A1DAOYTHDF3
SCHEMBL14656172 0.72 GPR84 (0.69) GPR84CA1ALDH1A1LMNACYP1A2
SCHEMBL60308 0.67
SCHEMBL8154152 0.66 GPR84 (0.38) GPR84CA1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL30618396 0.65 CA1 (0.95) GPR84CA1ALDH1A1LMNACYP1A2
Bromide SCHEMBL30618364 0.65 CA1 (0.95) GPR84CA1ALDH1A1LMNACYP1A2
SCHEMBL27323608 0.65 CA1 (0.95) GPR84CA1ALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106366677-A Anticorrosion wood-plastic composite profile and preparation method thereof 桂林舒康建材有限公司 2017-02-01 CN claimed
CN-103201355-B Flame retardant compositions comprising triazine-intercalated metal phosphates J.M.休伯有限公司 2016-08-17 CN claimed
CN-105315485-A Organic transparent compound heat stabilizer, as well as preparation method and application thereof UNIV ZHEJIANG TECHNOLOGY 2016-02-10 CN claimed
US-8067391-B2 ODCase inhibitors for the treatment of malaria UNIVERSITY HEALTH NETWORK (CA) 2011-11-29 US claimed
US-20090221524-A1 ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA UNIVERSITY HEALTH NETWORK (CA) 2009-09-03 US claimed
JP-7188023-A None JP disclosed
CN-107501807-B A kind of cold lamination film having highly resistance Ultraviolet Oxidation performance and anti-microbial property 浙江越千树数码科技有限公司 2019-08-27 CN disclosed
CN-107501807-A It is a kind of to possess high uvioresistant oxidation susceptibility and the cold lamination film of anti-microbial property 浙江越千树数码科技有限公司 2017-12-22 CN disclosed
CN-106366677-A Anticorrosion wood-plastic composite profile and preparation method thereof 桂林舒康建材有限公司 2017-02-01 CN disclosed
EP-1931691-B1 ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA UNIV HEALTH NETWORK (CA) 2013-08-21 EP disclosed
US-8252490-B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition FUJIFILM CORPORATION (JP) 2012-08-28 US disclosed
US-8252490-B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition FUJIFILM CORPORATION (JP) 2012-08-28 US disclosed
US-20090017273-A1 PIGMENT DISPERSION LIQUID, CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed
EP-2013279-A1 DERIVATIVES OF PYRIMIDINES AS FLAME RETARDANTS Ciba Holding Inc. (CH) 2009-01-14 EP disclosed
WO-2008083465-A1 PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS UNIVERSITY HEALTH NETWORK (CA) 2008-07-17 WO disclosed
WO-2007128678-A1 DERIVATIVES OF PYRIMIDINES AS FLAME RETARDANTS CIBA HOLDING INC. (CH) 2007-11-15 WO disclosed
EP-0967209-B1 NH2-modified 6-aminouracils as stabilisers for halogen-containing polymers CROMPTON VINYL ADDITIVES GMBH (DE) 2003-01-08 EP disclosed
US-5859100-A FILMS, PIPES; NONSTAINING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-01-12 US disclosed
US-5859100-A FILMS, PIPES; NONSTAINING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-01-12 US disclosed
JP-H07188023-A VASCULARIZATION INHIBITOR TAIHO YAKUHIN KOGYO KK 1995-07-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221524-A1 ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA UMPS, UGDH, UPP1 GPR84 1000/4885CA1 4878/4885ALDH1A1 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.