SCHEMBL8155308

SCHEMBL8155308

CC1=Cc2c(cccc2-c2ccc(C(C)C)cc2)[CH]1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
PRKAB2 O43741 1/20 0.30
PRKAG1 P54619 1/20 0.30
PRKAA2 P54646 1/20 0.30
PRKAA1 Q13131 1/20 0.30
PRKAG3 Q9UGI9 1/20 0.30
PRKAG2 Q9UGJ0 1/20 0.30
PRKAB1 Q9Y478 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27479295 0.94 MEN1 (0.33) LMNAMEN1USP2MAPTKMT2A
SCHEMBL8462251 0.85 GRIA4 (0.33)
SCHEMBL7624416 0.84 ADORA3 (0.38) MEN1KMT2AACHE
SCHEMBL15163555 0.84 MEN1 (0.36) LMNAMEN1USP2MAPTKMT2A
SCHEMBL27392580 0.83 PTGS2 (0.38) MEN1KMT2A
SCHEMBL27706992 0.83 ADORA3 (0.37) MEN1KMT2A
SCHEMBL27757770 0.83 MEN1 (0.35) LMNAMEN1USP2MAPTKMT2A
SCHEMBL60836 0.81 PDCD1 (0.39) LMNAACHE
SCHEMBL20548534 0.80 PDCD1 (0.38) LMNAACHE
SCHEMBL27478124 0.80 PDCD1 (0.38) LMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169900-C Adhesive resin composition and laminate made using same as adhesive layer ������ѧ��ʽ���� 2004-10-06 CN disclosed
CN-1098887-C Shrinkable film made from olefine copolymer MITSUI CHEMICALS INC (JP) 2003-01-15 CN disclosed
CN-1092208-C Ethylene copolymer rubber, sulphurable rubber combination containing copolymer rubber and preparation process for same MITSUI PETROCHEMICAL IND (JP) 2002-10-09 CN disclosed
EP-1054914-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND Basell Polyolefine GmbH (DE) 2000-11-29 EP disclosed
WO-2000035973-A1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND WHICH CONTAINS BORON TARGOR GMBH (DE) 2000-06-22 WO disclosed
EP-0942938-A1 SUPPORTED CATALYST SYSTEM, METHOD FOR THE PRODUCTION AND USE THEREOF IN OLEFIN POLYMERIZATION Basell Polyolefine GmbH (DE) 1999-09-22 EP disclosed
CN-1216057-A Adhesive resin composition and laminate using the same as adhesive layer MITSUI CHEMICALS INC (JP) 1999-05-05 CN disclosed
CN-1208050-A Olefin thermoplastic elastomer composition MITSUI CHEMICALS INC (JP) 1999-02-17 CN disclosed
CN-1206026-A Unsaturated elastomer compositions and their vulcanized MITSUI CHEMICALS INC (JP) 1999-01-27 CN disclosed
WO-1998040416-A1 SUPPORTED CATALYST SYSTEM, METHOD FOR THE PRODUCTION AND USE THEREOF IN OLEFIN POLYMERIZATION TARGOR GMBH (DE) 1998-09-17 WO disclosed
CN-1139676-A Ethylene copolymer rubber, sulphurable rubber combination containing copolymer rubber and preparation process for same MITSUI PETROCHEMICAL IND (JP) 1997-01-08 CN disclosed