Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573171 | 0.88 | — | — | |
| SCHEMBL2997479 | 0.88 | — | — | |
| SCHEMBL30829428 | 0.84 | — | — | |
| SCHEMBL5613333 | 0.84 | — | — | |
| SCHEMBL10571663 | 0.84 | — | — | |
| SCHEMBL8308112 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL6809972 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL6806491 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL11148340 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL21811591 | 0.75 | PRKCA (0.34) | ALDH1A1TDP1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |