Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | TNF | P01375 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622742 | 1.00 | ALDH1A1 (0.63) | ALDH1A1TP53TDP1MAPTKDM4E | |
| Anthranilic Acid SCHEMBL10434164 | 0.88 | MAPT (0.58) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL7224097 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL1805998 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL15248025 | 0.83 | CYP3A4 (0.50) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL99697 | 0.83 | CASP1 (0.63) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL2553178 | 0.81 | CYP3A4 (0.48) | ALDH1A1TP53TDP1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11630591 | 0.81 | CASP1 (0.61) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL1099858 | 0.81 | CYP3A4 (0.48) | ALDH1A1TP53TDP1MAPTKDM4E | |
| SCHEMBL29364937 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924202-A | Chrome-free tanning agent containing carboxylic acid sulfonate structure and preparation method thereof | 浙江康诺和新材料有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117720426-A | Synthesis method of 2-amino-5-chloro-3-methylbenzoic acid | 湖北泰盛化工有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117449033-A | Dustproof antistatic acoustic mesh cloth and preparation method thereof | 江阴市恒宇网业有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116730876-A | Hapten, complete antigen, artificial antigen and antibody of urea herbicide, preparation method and application thereof | 深圳市质量安全检验检测研究院(深圳市动物疫病预防控制中心) | 2023-09-12 | — | — | CN | claimed |
| CN-106748721-B | A kind of preparation method of the chloro- 5- iodo-benzoic acid of 2- | 山东铂源药业有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-106748721-A | A kind of preparation method of the iodo-benzoic acid of 2 chlorine 5 | 山东铂源药业有限公司 | 2017-05-31 | — | — | CN | claimed |
| JP-4790179-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| EP-2305246-A1 | Tumor necrosis factor inhibitors | Ception Therapeutics, Inc. (US) | 2011-04-06 | — | — | EP | claimed |
| EP-2298295-A1 | Tumor necrosis factor inhibitors | Ception Therapeutics, Inc. (US) | 2011-03-23 | — | — | EP | claimed |
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | CEPTION THERAPEUTICS, INC. (US) | 2009-09-03 | — | — | US | claimed |
| CN-1477099-A | O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same | 百瑞全球有限公司 | 2004-02-25 | — | — | CN | claimed |
| US-6555175-B2 | Process for the surface modification of a polymeric substrate | Johnson, Joseph E. | 2003-04-29 | — | — | US | claimed |
| JP-2003505503-A | — | — | 2003-02-12 | — | — | JP | claimed |
| EP-1207873-A1 | METHODS OF INHIBITING OSTEOCLAST ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001008677-A1 | METHODS OF INHIBITING OSTEOCLAST ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2001-02-08 | — | — | WO | claimed |
| EP-0705316-B1 | EPOXY ADHESIVE COMPOSITION | MINNESOTA MINING & MFG (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0705316-A1 | EPOXY ADHESIVE COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-10 | — | — | EP | claimed |
| US-5280067-A | Heat curable adhesive | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-01-18 | — | — | US | claimed |
| WO-1994000527-A1 | EPOXY ADHESIVE COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-01-06 | — | — | WO | claimed |
| US-5075361-A | Solubilizers | TEXACO INC. (US) | 1991-12-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221527-A1 | TUMOR NECROSIS FACTOR INHIBITORS | TNFRSF1A, TNF, TNFRSF9 | ALDH1A1 3912/4885TP53 52/4885TDP1 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.