Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218589 | 0.88 | CASP1 (0.47) | ALDH1A1TP53TDP1KDM4EMAPT | |
| SCHEMBL29622742 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TP53TDP1KDM4EMAPT | |
| SCHEMBL81564 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TP53TDP1KDM4EMAPT | |
| Anthranilic Acid SCHEMBL10434164 | 0.74 | MAPT (0.58) | ALDH1A1TP53TDP1KDM4EMAPT | |
| SCHEMBL1805998 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TP53TDP1KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL7222237 | 0.73 | TSHR (0.46) | ALDH1A1TP53MAPTCYP3A4HPGD | |
| SCHEMBL1099858 | 0.72 | CYP3A4 (0.48) | ALDH1A1TP53TDP1KDM4EMAPT | |
| 3-Aminobenzoic Acid SCHEMBL7218839 | 0.71 | PBRM1 (0.51) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| Carbamic Acid SCHEMBL9949893 | 0.71 | CASP1 (0.59) | ALDH1A1TP53TDP1KDM4EMAPT | |
| SCHEMBL15248025 | 0.70 | CYP3A4 (0.50) | ALDH1A1TP53TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525061-B1 | Combinatorial libraries for drug discovery;4-((6-bromo-4-oxo-1,4-dihydroquinazolin-2-yl)amino)b enzoic acid, | WYETH | 2003-02-25 | — | — | US | disclosed |
| US-20020049320-A1 | 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049320-A1 | 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof | DAZAP1, DCUN1D5, DHX15 | ALDH1A1 127/4885TP53 3427/4885TDP1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.