Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156486 | 0.84 | PTGER4 (0.55) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL689666 | 0.81 | CYP19A1 (0.64) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL28392221 | 0.79 | P2RX4 (0.61) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL4780793 | 0.79 | PTGER4 (0.55) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL4780075 | 0.79 | PTGER4 (0.50) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL30676985 | 0.77 | PTGER4 (0.55) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL689732 | 0.77 | PTGER4 (0.55) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL4793098 | 0.77 | CYP11B1 (0.44) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL4793959 | 0.76 | PTGER4 (0.55) | PTGER4CYP19A1HDAC6PSMD14LMNA | |
| SCHEMBL4794184 | 0.75 | PTGER4 (0.54) | PTGER4CYP19A1HDAC6PSMD14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |