Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474040 | 0.89 | — | — | |
| SCHEMBL14503187 | 0.86 | ACE (0.55) | ACEHAO1TSHRKDM4EKDM6B | |
| SCHEMBL1701664 | 0.86 | CES2 (0.53) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL3126473 | 0.83 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL5667473 | 0.83 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL11434918 | 0.83 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL29053185 | 0.83 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL534886 | 0.81 | CES1 (0.52) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL8101925 | 0.80 | CES2 (0.47) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL5273375 | 0.79 | HAO1 (0.61) | CES2CES1HAO1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824763-B1 | POLYMER ELECTROLYTE COMPOSITION BASED UPON THIOL-ENE CHEMISTRY | MINNESOTA MINING & MFG (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-0824763-A1 | POLYMER ELECTROLYTE COMPOSITION BASED UPON THIOL-ENE CHEMISTRY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035238-A1 | POLYMER ELECTROLYTE COMPOSITION BASED UPON THIOL-ENE CHEMISTRY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-11-07 | — | — | WO | disclosed |