Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19453667 | 0.88 | ALDH1A1 (0.36) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL8230038 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL8198754 | 0.75 | NPSR1 (0.38) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL19453304 | 0.75 | GLO1 (0.34) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL10051280 | 0.72 | NPSR1 (0.38) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL14205772 | 0.70 | NPSR1 (0.36) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL6531427 | 0.69 | NPSR1 (0.42) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL18436700 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL8204396 | 0.68 | NPSR1 (0.33) | ALDH1A1TSHRNPSR1GLO1 | |
| SCHEMBL16410842 | 0.68 | NPSR1 (0.41) | ALDH1A1TSHRNPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109994-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-09-18 | — | — | WO | disclosed |