Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156981 | 1.00 | TSHR (0.39) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL7697578 | 0.77 | FAAH (0.35) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL7697580 | 0.77 | FAAH (0.35) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL1785190 | 0.76 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL14489225 | 0.74 | FAAH (0.33) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL1784663 | 0.74 | TSHR (0.52) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL1783206 | 0.74 | TSHR (0.59) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL27785813 | 0.73 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL27355281 | 0.72 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL7700905 | 0.72 | ACLY (0.32) | FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056716-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043646-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |