Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150832 | 0.91 | PIK3CD (0.45) | FAAHMGLLNAAAALDH1A1TSHR | |
| SCHEMBL8158607 | 0.90 | MGLL (0.43) | FAAHMGLLNAAAALDH1A1TSHR | |
| SCHEMBL9250191 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL419534 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL14184720 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL8512828 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL27992732 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL4860823 | 0.87 | NAAA (0.54) | FAAHMGLLNAAAKDM4EALDH1A1 | |
| SCHEMBL10337812 | 0.86 | KDM4E (0.39) | FAAHMGLLNAAAKDM4ETRPV1 | |
| SCHEMBL31308 | 0.85 | NAAA (0.51) | FAAHMGLLNAAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086905-A | Topical compositions useful as skin penetration barriers | DISCOVERY THERAPEUTICS, INC. | 2000-07-11 | — | — | US | disclosed |