Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158310 | 0.95 | ALOX5 (0.42) | KDM4EALDH1A1MEN1KMT2AEGFR | |
| SCHEMBL8150987 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2AEGFR | |
| SCHEMBL8157433 | 0.77 | APEX1 (0.39) | KDM4EALDH1A1ALOX5POLBAPEX1 | |
| SCHEMBL8150707 | 0.77 | POLB (0.53) | EGFRERBB2AKR1B10AKR1B1POLB | |
| SCHEMBL8144687 | 0.76 | ESR1 (0.41) | KDM4EALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL8157453 | 0.76 | APP (0.49) | ALOX5AKR1B10AKR1B1SMN1; SMN2APP | |
| SCHEMBL8150963 | 0.76 | MAPT (0.41) | KDM4EALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL8151215 | 0.75 | CA12 (0.48) | EGFRERBB2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL8158313 | 0.74 | ALOX5 (0.35) | ALDH1A1MEN1KMT2AALOX5POLB | |
| SCHEMBL8150942 | 0.74 | APP (0.43) | ALOX5TSHRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |