Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157427 | 0.95 | KDM4E (0.41) | ALOX5KDM4EMEN1KMT2AEGFR | |
| SCHEMBL8150987 | 0.81 | ALDH1A1 (0.46) | ALOX5KDM4EMEN1KMT2AEGFR | |
| SCHEMBL18373551 | 0.79 | ALOX5 (0.44) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL8157283 | 0.77 | NFE2L2 (0.59) | ALOX5KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8143776 | 0.77 | MAPK1 (0.54) | ALOX5KDM4EMEN1KMT2AEGFR | |
| SCHEMBL8158313 | 0.76 | ALOX5 (0.35) | ALOX5MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8157078 | 0.76 | POLB (0.56) | EGFRERBB2AKR1B10AKR1B1SMN1; SMN2 | |
| SCHEMBL8152922 | 0.75 | APP (0.47) | ALOX5KDM4EMEN1KMT2AEGFR | |
| SCHEMBL8157086 | 0.75 | ESR1 (0.43) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL3085092 | 0.75 | AKR1B10 (0.64) | ALOX5KDM4EMEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |