⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336375 | 1.00 | — | — | |
| SCHEMBL13619240 | 0.83 | — | — | |
| SCHEMBL1777394 | 0.81 | — | — | |
| SCHEMBL17787236 | 0.79 | CTSK (0.31) | — | |
| SCHEMBL9304034 | 0.79 | APLNR (0.33) | — | |
| SCHEMBL5633650 | 0.79 | APLNR (0.33) | — | |
| SCHEMBL2160578 | 0.79 | APLNR (0.33) | — | |
| SCHEMBL15508219 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL19361679 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL31692787 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809566-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-11-07 | — | — | US | disclosed |
| US-9809566-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-11-07 | — | — | US | disclosed |
| US-9765048-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-09-19 | — | — | US | disclosed |
| US-20160272608-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-20160272608-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-20160272609-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-20160272609-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-9353077-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-31 | — | — | US | disclosed |
| US-9353077-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-31 | — | — | US | disclosed |
| US-20150210665-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-30 | — | — | US | disclosed |
| US-8921414-B2 | Spiroketals | ECOBIOTICS LTD (AU) | 2014-12-30 | — | — | US | disclosed |
| US-20140286938-A1 | SPIROKETALS | ECOBIOTICS LTD (AU) | 2014-09-25 | — | — | US | disclosed |
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |
| WO-2000000514-A9 | SYNTHETIC SPIROKETAL PYRANES AS POTENT ANTI-CANCER AGENTS | PARKER HUGHES INST (US) | 2000-07-20 | — | — | WO | disclosed |