SCHEMBL815783

SCHEMBL815783

COC(=O)C(F)(F)C(F)(F)CCC(F)(F)C(F)(F)CCC(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814270 0.83 ALDH1A1 (0.34) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL11207116 0.76 DGAT1 (0.33) ALDH1A1GAADGAT1
SCHEMBL1129794 0.74 ALDH1A1 (0.42) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL23882165 0.74 ALDH1A1 (0.32) ALDH1A1GAADGAT1
SCHEMBL517250 0.74 ALDH1A1 (0.45) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL814625 0.73 THRB (0.42)
Ammonia Solution, Strong SCHEMBL814267 0.71 THRB (0.41)
SCHEMBL2429597 0.71 CA1 (0.31) MEN1KMT2A
SCHEMBL2492481 0.70 ALDH1A1 (0.39) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL2429786 0.70 CA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8058375-B2 Use of ethylene-tetrafluoroethylene carboxylic acids and salts as surfactants for aqueous emulsion polymerization of fluorinated monomer E I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-15 US disclosed
EP-2370392-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
WO-2010075354-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
US-20100160550-A1 USE OF ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS AS SURFACTANTS FOR AQUEOUS EMULSION POLYMERIZATION OF FLUORINATED MONOMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
US-20100160584-A1 Ethylene-Tetrafluoroethylene Carboxylic Acids and Salts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed