Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157290 | 0.94 | MAPT (0.41) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8158364 | 0.84 | TDP1 (0.39) | TDP1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL8157860 | 0.82 | GLO1 (0.52) | ALDH1A1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL8158566 | 0.79 | ALDH1A1 (0.43) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8551386 | 0.79 | MAPT (0.40) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8153015 | 0.79 | MAPT (0.43) | ALDH1A1MAPTMAPK1HTTKMT2A | |
| SCHEMBL8156926 | 0.77 | MEN1 (0.40) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL11028205 | 0.77 | ALDH1A1 (0.63) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8157287 | 0.77 | STAT3 (0.44) | TDP1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL11026162 | 0.77 | ALDH1A1 (0.56) | TDP1ALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |