Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154514 | 0.76 | ADORA2A (0.43) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL8146115 | 0.69 | ADORA2A (0.45) | ADORA2AADORA2BADORA1TMIGD3CDK1 | |
| SCHEMBL4948136 | 0.66 | PDGFRA (0.44) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL7209426 | 0.65 | PDE4A (0.60) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL28689869 | 0.62 | DDB1 (0.51) | — | |
| SCHEMBL19302902 | 0.62 | ADORA2A (0.58) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL19302903 | 0.61 | PDE5A (0.52) | ADORA2ACYP1A2ADORA2BTHPOADORA1 | |
| SCHEMBL8146043 | 0.61 | CTSL (0.63) | ADORA2AADORA2BADORA1TMIGD3CDK2 | |
| SCHEMBL9021635 | 0.60 | ADORA2A (0.82) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL9021653 | 0.60 | ADORA2A (0.82) | ADORA2ACYP1A2ADORA2BTHPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | claimed |