Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154514 | 0.79 | ADORA2A (0.43) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL8153955 | 0.79 | TK1 (0.58) | — | |
| SCHEMBL5801330 | 0.73 | HDAC3 (0.40) | — | |
| SCHEMBL8158951 | 0.69 | ADORA2A (0.40) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL19690966 | 0.68 | CDK1 (0.45) | CDK1 | |
| SCHEMBL12396113 | 0.68 | TMIGD3 (0.41) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL8146043 | 0.67 | CTSL (0.63) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL2160243 | 0.67 | FGFR1 (0.47) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL8146595 | 0.67 | — | — | |
| SCHEMBL19691015 | 0.67 | KCNN2 (0.51) | CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | claimed |
| EP-0772439-B1 | Novel antibiotic compounds and antibiotic compositions comprising said compounds for inhibiting gram positive bacteria and mycoplasma cells. | UNIV MASSACHUSETTS MEDICAL (US) | 2000-10-04 | — | — | EP | disclosed |
| EP-0772439-A4 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0772439-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5516905-A | ENZYME INHIBITORS OF DNA POLYMERASE FOR BACTERICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-05-14 | — | — | US | disclosed |
| WO-1996006614-A1 | NOVEL ANTIBIOTIC COMPOUNDS AND METHODS TO TREAT GRAM-POSITIVE BACTERIAL AND MYCOPLASMAL INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-03-07 | — | — | WO | disclosed |