Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159554 | 0.92 | HTT (0.38) | KMT2AHTTALDH1A1KDM4ELMNA | |
| SCHEMBL8160025 | 0.86 | AKR1C3 (0.37) | ALDH1A1KDM4EMAPK1L3MBTL1TSHR | |
| SCHEMBL8153179 | 0.85 | ABCB1 (0.42) | KMT2AHTTKDM4ELMNAL3MBTL1 | |
| SCHEMBL8159064 | 0.85 | PTGES (0.39) | ALDH1A1LMNAMAPK1L3MBTL1TSHR | |
| SCHEMBL8159445 | 0.84 | PTPN11 (0.39) | KMT2AALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL8152034 | 0.83 | PTPN11 (0.41) | KMT2AALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL8146381 | 0.79 | MEN1 (0.50) | KMT2AHTTLMNAMAPK1L3MBTL1 | |
| SCHEMBL8146380 | 0.79 | MEN1 (0.50) | KMT2AHTTLMNAMAPK1L3MBTL1 | |
| SCHEMBL8158807 | 0.78 | ALDH1A1 (0.38) | KMT2AALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL8154299 | 0.77 | ALOX5 (0.41) | KMT2AALDH1A1LMNAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |