SCHEMBL8159090

SCHEMBL8159090

CC(c1ccc2c(c1)C=CC2)c1ccc2c(c1)C=CC2

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
PDCD1 Q15116 1/20 0.32
ESR2 Q92731 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7184341 0.88 CA1 (0.30) CA1CA2
SCHEMBL6912483 0.88 LMNA (0.36) CA1CA2
SCHEMBL12087022 0.78 PDE2A (0.32)
SCHEMBL4464105 0.76 MEN1 (0.31)
SCHEMBL924413 0.72 CYP1A2 (0.35) CA1CA2
SCHEMBL6912121 0.72 LMNA (0.36)
SCHEMBL6911079 0.72 GABRA1 (0.41) ESR1
SCHEMBL9629684 0.72 CA1 (0.34) CA1CA2
SCHEMBL275807 0.70 CA1 (0.33) CA1CA2
SCHEMBL10400380 0.69 ESR1 (0.40) ESR1PDCD1ESR2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1034190-A1 POLYMERIZATION CATALYST FOR OLEFIN MONOMERS LG CHEMICAL LIMITED (KR) 2000-09-13 EP disclosed
WO-1999026985-A1 POLYMERIZATION CATALYST FOR OLEFIN MONOMERS LG CHEMICAL LTD. (KR) 1999-06-03 WO disclosed