Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159369 | 1.00 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL8081928 | 1.00 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL29246850 | 1.00 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL9560007 | 0.84 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL30084103 | 0.84 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL30084108 | 0.84 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL10991428 | 0.80 | LMNA (0.43) | LMNAALDH1A1TP53CACNA1C | |
| SCHEMBL11052010 | 0.80 | LMNA (0.49) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL29246833 | 0.79 | GBA1 (0.30) | — | |
| SCHEMBL15978554 | 0.79 | GBA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6072074-A | Process for producing 3-propynyl-2-2-dimethylcycloprophane-carboxylic acid and its lower akyl esters | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0955287-A1 | Propynyl compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-11-10 | — | — | EP | disclosed |